Friday, September 20, 2013

Dosages and Soporific Spells

Let us be clear:

When it comes to flying ointments, potions, etc., and tropane producing plants:

- The alkaloid content of the plant is variable.

It depends on when you plant it, when you uproot it, and a number of other potential factors.

- You cannot measure the alkaloid content of the tropane producing nightshades if you do not test them in a lab.

Anyone that seems to indicate otherwise is wrong. There are 'tricks' for hopefully avoiding an alkaloid heavy plant, but they remain risky. The only way to be sure is to have the plant matter analyzed by those with the skills to do so, in a lab outfitted with the proper equipment.

- Some plants have a higher content of specific tropanes versus their relatives.

- The tropane content of the plant also varies depending on the area of the plant being used.

In some plants, the roots contain fewer tropane alkaloids than in others.

- Fuck up, and you may die.

- When medieval surgeons used the soporific sponge, sometimes people died.

This occurred because they often couldn't accurately measure the dosage of the alkaloids. Their 'dosages' consisted of the amount of plant matter applied together, which failed to take into account the true danger of the plants: that you don't know precisely how potent the sponge would be.

In theory, application to the skin versus ingestion decreases the amount of tropane alkaloids that pass into the blood stream and then cross the blood-brain barrier to affect the acetylcholine receptors. But, again, this is not exactly a sure method. There are still factors such as:
- Whether or not the person is taking drugs or medicine for a medical or psychological condition.

- Whether or not the person has, for example, ingested a compound which will increase the effectiveness of the the tropane compounds within the body.

Additionally, just like the tropane alkaloids can be stored in fats for a flying ointment, they are stored in the body's fat cells. This can be... problematic, particularly if the content becomes too high.

There are, of course, also mitigating factors. But they do not relate to the exact measurement of the plants being used in the ointment, nor to the application of the ointment on the body. They relate rather directly to the mitigating actions of the secondary metabolites of other plants, and with the variable content again being an issue they are hardly tried and true.

In short? Be careful. And unless someone happens to have a lab they can test the plants in? They may not actually know how powerful the thing in their hands is. This isn't a laughing matter.

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